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However, another finding suggested that G6PD expression and activity are elevated in the SN both in vitro and in vivo in PD, and that inhibition of G6PD and knockdown of microglial G6PD significantly attenuated LPS-induced dopaminergic neurodegeneration [118]

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Xia, M., et al., Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R--lipoic acid by next-generation sequencing